Brief Information of the Compound and Protein
Compound Name
N-[2-methoxy-5-[5-(6-methyl-7-oxo-5H-pyrrolo[3,4-b]pyridin-3-yl)thiophen-2-yl]pyridin-3-yl]-2-nitrobenzenesulfonamide
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PubChem ID
CID: 155512068
Canonical SMILES
COc1ncc(cc1NS(=O)(=O)c1ccccc1[N+]([O-])=O)-c1ccc(s1)-c1cnc2C(=O)N(C)Cc2c1
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Compound Formula C24H19N5O6S2
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
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Other ion channel
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Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CL000975 KHYG-1 Homo sapiens (Human)  1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS