Brief Information of the Compound and Protein
Compound Name
3-[1-(2-chloro-5-fluorophenyl)ethoxy]-5-phenylpyridin-2-amine
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PubChem ID
CID: 146185154
Canonical SMILES
CC(Oc1cc(cnc1N)-c1ccccc1)c1cc(F)ccc1Cl
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Compound Formula C19H16ClFN2O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 461 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 461 nM