Brief Information of the Compound and Protein
Compound Name
2-amino-9-[(1R,6R,8R,9R,10S,15R,17R,18R)-3,9,12,18-tetrahydroxy-8-[6-(methylamino)purin-9-yl]-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.2.1.06,10]octadecan-17-yl]-1H-purin-6-one
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PubChem ID
CID: 137132410
Canonical SMILES
CNc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]3n1cnc2c1nc(N)[nH]c2=O
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Compound Formula C21H26N10O13P2
Compound Structure
Protein Name
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  4
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
2
EC50 = 60 nM
   TI
   LI
   LO
   TS
3
EC50 = 1200 nM
   TI
   LI
   LO
   TS
4
EC50 = 63700 nM
   TI
   LI
   LO
   TS