Brief Information of the Compound and Protein
Compound Name
N-[2-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
    Show/Hide
PubChem ID
CID: 155553696
Canonical SMILES
COc1cc(ccc1Nc1ncc(c(n1)N1Cc2cccc(N(C)S(C)(=O)=O)c2C1)C(F)(F)F)N1CCN(CC1)C(C)=O
    Show/Hide
Compound Formula C28H32F3N7O4S
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
P30530
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 790 nM
   TI
   LI
   LO
   TS