Brief Information of the Compound and Protein
Compound Name
N-[2-[2-(3,5-dimethoxyanilino)-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
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PubChem ID
CID: 155525863
Canonical SMILES
COc1cc(Nc2ncc(c(n2)N2Cc3cccc(N(C)S(C)(=O)=O)c3C2)C(F)(F)F)cc(OC)c1
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Compound Formula C23H24F3N5O4S
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
P30530
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS