Brief Information of the Compound and Protein
Compound Name
1-(2,6-dibromo-4-propan-2-ylphenyl)-3-pyridin-3-ylurea
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PubChem ID
CID: 2810999
Canonical SMILES
CC(C)c1cc(Br)c(NC(=O)Nc2cccnc2)c(Br)c1
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Compound Formula C15H15Br2N3O
Compound Structure
Protein Name
P2X purinoceptor 4
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99571
Gene Name
P2RX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  2
1
IC50 = 904 nM
   TI
   LI
   LO
   TS
2
IC50 = 1950 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
2
IC50 = 780 nM
   TI
   LI
   LO
   TS