Brief Information of the Compound and Protein
Compound Name
7-[2-[benzyl-[[1-[2-[2-[2-(4-oxo-2-phenylchromen-7-yl)oxyethoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
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PubChem ID
CID: 89784733
Canonical SMILES
O=c1cc(oc2cc(OCCOCCOCCn3cc(CN(CCOc4ccc5c(c4)oc(cc5=O)-c4ccccc4)Cc4ccccc4)nn3)ccc12)-c1ccccc1
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Compound Formula C48H44N4O8
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000462 HEKR2 Homo sapiens (Human)  1
1
EC50 = 54 nM
   TI
   LI
   LO
   TS
CL000415 MCF-7 MX100 Homo sapiens (Human)  1
1
EC50 = 58 nM
   TI
   LI
   LO
   TS