Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-[(3R)-3-aminopiperidine-1-carbonyl]-5-methyl-1-(4-methylphenyl)imidazol-2-yl]benzonitrile
    Show/Hide
 PubChem ID
CID: 118626664
Canonical SMILES
Cc1c(nc(-c2ccc(cc2)C#N)n1-c1ccc(C)cc1)C(=O)N1CCC[C@@H](N)C1
    Show/Hide
Compound Formula C24H25N5O
Compound Structure
Protein Name
 Protein Info 
Lysine-specific histone demethylase 1A
Protein Classification
Epigenetic regulator
>
Eraser
>
Lysine demethylase
>
Lysine-specific demethylase
Uniprot ID
O60341
Gene Name
KDM1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM