Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-[3,5-difluoro-4-[(1R,12S)-16-(2-fluoro-2-methylpropyl)-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8,13-pentaen-1-yl]phenyl]prop-2-enoic acid
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 PubChem ID
CID: 155566549
Canonical SMILES
CC(C)(F)CN1[C@H]2Cc3c([nH]c4ccccc34)[C@@]1(CC=C2)c1c(F)cc(\C=C\C(O)=O)cc1F
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Compound Formula C27H25F3N2O2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.585 nM
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