Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,12R)-1-[2,6-difluoro-4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenyl]-16-(2-fluoro-2-methylpropyl)-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene
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 PubChem ID
CID: 155540121
Canonical SMILES
CC(C)(F)CN1[C@@H]2CCC[C@]1(c1[nH]c3ccccc3c1C2)c1c(F)cc(OCCN2CC(CF)C2)cc1F
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Compound Formula C30H35F4N3O
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.995 nM
   TI
   LI
   LO
   TS