Brief Information of the Compound and Protein
Compound Name
5-[3-(difluoromethyl)-5-fluoropyridin-2-yl]-5-methoxy-8-oxospiro[2.5]oct-6-ene-7-carbonitrile
    Show/Hide
PubChem ID
CID: 155529372
Canonical SMILES
COC1(CC2(CC2)C(=O)C(=C1)C#N)c1ncc(F)cc1C(F)F
    Show/Hide
Compound Formula C16H13F3N2O2
Compound Structure
Protein Name
Kelch-like ECH-associated protein 1
Protein Classification
Unclassified protein
Uniprot ID
Q14145
Gene Name
KEAP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS