Brief Information of the Compound and Protein
Compound Name
2-[[7-[(2R,3R,4S,5R)-5-[(R)-(4-chlorophenyl)-hydroxymethyl]-3,4-dihydroxyoxolan-2-yl]pyrrolo[2,3-d]pyrimidin-4-yl]amino]acetaldehyde
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PubChem ID
CID: 138753159
Canonical SMILES
O[C@@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(NCC=O)ncnc12)c1ccc(Cl)cc1
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Compound Formula C19H19ClN4O5
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000152 Granta-519 Homo sapiens (Human)  1
1
IC50 = 22 nM
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