Brief Information of the Compound and Protein
Compound Name
3-(4-methoxyphenyl)-9-morpholin-4-ylsulfonyl-1-oxo-6,11a-dihydroindolo[3,2-b]quinoxaline-2,4-dicarbonitrile
    Show/Hide
Canonical SMILES
COc1ccc(cc1)C1=C(C#N)C2=NC3=Nc4ccc(cc4C3=NC2C(O)=C1C#N)S(=O)(=O)N1CCOCC1
    Show/Hide
Compound Formula C27H20N6O5S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS