Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8552004, 2.03
    Show/Hide
 PubChem ID
CID: 54761473
SID: 131525579
Canonical SMILES
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)cc(C2([S@](C)(=N)=O)CC2)n1
    Show/Hide
Compound Formula C21H27N7O2S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
2
IC50 = 9800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 150 nM