Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-methyl-1-[4-[(3R)-3-methylmorpholin-4-yl]-6-(1-methylsulfonylcyclopropyl)pyrimidin-2-yl]benzimidazol-2-amine
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 PubChem ID
CID: 145987142
Canonical SMILES
CNc1nc2ccccc2n1-c1nc(cc(n1)C1(CC1)S(C)(=O)=O)N1CCOC[C@H]1C
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Compound Formula C21H26N6O3S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
2
IC50 = 4000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 52 nM