Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R)-3-methyl-4-[6-(1-methylsulfonylcyclopropyl)-2-(1H-pyrrolo[2,3-c]pyridin-4-yl)pyrimidin-4-yl]morpholine
    Show/Hide
 PubChem ID
CID: 145981271
Canonical SMILES
C[C@@H]1COCCN1c1cc(nc(n1)-c1cncc2[nH]ccc12)C1(CC1)S(C)(=O)=O
    Show/Hide
Compound Formula C20H23N5O3S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 270 nM
   TI
   LI
   LO
   TS
2
IC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM