Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
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 PubChem ID
CID: 110635
SID: 14756405
Canonical SMILES
CN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O
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Compound Formula C22H19N3O4
Compound Structure
Protein Name
 Protein Info 
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 11
>
Phosphodiesterase 11A
Uniprot ID
Q9HCR9
Gene Name
PDE11A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 22.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 37 nM
   TI
   LI
   LO
   TS
3
IC50 = 47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM
2 IC50 = 33 nM
3 IC50 = 50 nM
4 IC50 = 290 nM
5 IC50 = 300 nM
6 IC50 = 60000 nM