Brief Information of the Compound and Protein
Compound Name
US10239843, Example 192
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PubChem ID
CID: 121398362
Canonical SMILES
Cc1cc(Cn2c3ccc(cc3c(=O)n(CC#N)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1
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Compound Formula C20H22N6O4S
Compound Structure
Protein Name
Poly(ADP-ribose) glycohydrolase
Protein Classification
Enzyme
Uniprot ID
Q86W56
Gene Name
PARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 560 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 280 nM