Brief Information of the Compound and Protein
Compound Name
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide
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PubChem ID
CID: 145991710
Canonical SMILES
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nsnc1O
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Compound Formula C11H5F6N3O2S
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
Uniprot ID
O14920
Gene Name
IKBKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 143 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 100000 nM