Brief Information of the Compound and Protein
Compound Name
6-chloro-N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-nitropyridin-2-amine
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PubChem ID
CID: 145993995
Canonical SMILES
[O-][N+](=O)c1ccc(Cl)nc1Nc1ncc(cc1Cl)C(F)(F)F
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Compound Formula C11H5Cl2F3N4O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
IC50 = 32 nM
   TI
   LI
   LO
   TS
3
IC50 = 53 nM
   TI
   LI
   LO
   TS
4
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 53 nM