Brief Information of the Compound and Protein
Compound Name
CHEBI:63453
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PubChem ID
CID: 51039095
SID: 136350053
Canonical SMILES
COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1
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Compound Formula C26H33N5O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 56 nM
   TI
   LI
   LO
   TS
2
IC50 = 67 nM
   TI
   LI
   LO
   TS
3
IC50 = 103 nM
   TI
   LI
   LO
   TS
4
IC50 = 655 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 45.7 nM
2 IC50 = 49.8 nM
3 IC50 = 56 nM
4 IC50 = 165 nM
5 IC50 = 2510 nM