Brief Information of the Compound and Protein
Compound Name
N-(4-fluoro-2-(trifluoromethyl)benzyl)-N-methyl-1-(4-(1-methyl-1Hpyrazol-5-yl)phthalazin-1-yl)piperidin-4-amine
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PubChem ID
CID: 86343736
Canonical SMILES
CN(Cc1ccc(F)cc1C(F)(F)F)C1CCN(c2nnc(-c3ccnn3C)c3ccccc23)CC1
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Compound Formula C26H26F4N6
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 68.5 nM
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