Brief Information of the Compound and Protein
Compound Name
2-chloro-4-[2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyloxan-4-yl)pyrazol-3-yl]pyridine
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PubChem ID
CID: 73293610
Canonical SMILES
COc1ccccc1-n1nc(cc1-c1ccnc(Cl)c1)C1CC(C)(C)OC(C)(C)C1
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Compound Formula C24H28ClN3O2
Compound Structure
Protein Name
Voltage-dependent N-type calcium channel subunit alpha-1B
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
Q00975
Gene Name
CACNA1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
2
IC50 = 250 nM
   TI
   LI
   LO
   TS
3
IC50 = 740 nM
   TI
   LI
   LO
   TS