Brief Information of the Compound and Protein
Compound Name
3,4-dichloro-2-ethoxy-N-(2,2,6,6-tetramethylpiperidin-4-yl)benzenesulfonamide
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PubChem ID
CID: 1257937
Canonical SMILES
CCOc1c(S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)ccc(Cl)c1Cl
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Compound Formula C17H26Cl2N2O3S
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
Uniprot ID
O14920
Gene Name
IKBKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 35400 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 32700 nM
   TI
   LI
   LO
   TS
2
IC50 = 55800 nM
   TI
   LI
   LO
   TS
CL000730 SK-N-AS Homo sapiens (Human)  1
1
IC50 = 56100 nM
   TI
   LI
   LO
   TS