Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8952169, 6
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 PubChem ID
CID: 72545669
Canonical SMILES
CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC23CC4CC(CC(C4)C2)C3)cc1F
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Compound Formula C19H23ClFNO4S
Compound Structure
Protein Name
 Protein Info 
Sodium channel protein type 9 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated sodium channel
Uniprot ID
Q15858
Gene Name
SCN9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.5 nM
   TI
   LI
   LO
   TS
3
IC50 = 6 nM
   TI
   LI
   LO
   TS
4
IC50 = 40 nM
   TI
   LI
   LO
   TS
5
IC50 = 70 nM
   TI
   LI
   LO
   TS
6
IC50 = 1370 nM
   TI
   LI
   LO
   TS
7
IC50 = 8870 nM
   TI
   LI
   LO
   TS
8
IC50 = 27350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.8 nM