Brief Information of the Compound and Protein
Compound Name
4-[[4-[[4-(4-cyano-2,6-dimethylphenoxy)-5-(phenylmethoxymethyl)pyrrolo[3,2-d]pyrimidin-2-yl]amino]piperidin-1-yl]methyl]benzamide
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PubChem ID
CID: 145980194
Canonical SMILES
Cc1cc(cc(C)c1Oc1nc(NC2CCN(Cc3ccc(cc3)C(N)=O)CC2)nc2ccn(COCc3ccccc3)c12)C#N
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Compound Formula C36H37N7O3
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  3
1
EC50 = 35.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 567 nM
   TI
   LI
   LO
   TS
3
IC50 = 158 nM
   TI
   LI
   LO
   TS