Brief Information of the Compound and Protein
Compound Name
3-[(Z)-[1-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)butyl]-2H-indol-3-ylidene]amino]-1,1-dimethylthiourea
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PubChem ID
CID: 145986644
Canonical SMILES
COc1cc2CCN(CCCCN3C\C(=N/NC(=S)N(C)C)c4ccccc34)Cc2cc1OC
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Compound Formula C26H35N5O2S
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000359 MDCK-MDR1 Canis lupus familiaris (Dog)  1
1
EC50 = 3040 nM
   TI
   LI
   LO
   TS