Brief Information of the Compound and Protein
| Compound Name |
N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Histone deacetylase 8
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Protein Classification |
Epigenetic regulator
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Eraser
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Histone deacetylase
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HDAC class I
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| Uniprot ID | Gene Name | HDAC8 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 3 |
| 1 |
IC50 = 330 nM
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TI
LI
LO
TS
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| 2 |
IC50 = 333 nM
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TI
LI
LO
TS
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| 3 |
IC50 = 854 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 681 nM | ||
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| 2 | IC50 = 695 nM | ||
| 3 | IC50 = 755 nM | ||
| 4 | IC50 = 814 nM | ||
| 5 | IC50 = 850 nM | ||
| 6 | IC50 = 854 nM | ||
| 7 | IC50 = 1270 nM | ||
| 8 | IC50 = 1899 nM | ||
| 9 | IC50 = 2340 nM | ||
| 10 | IC50 > 5000 nM | ||
| 11 | Ki = 96.2 nM | ||