Brief Information of the Compound and Protein
Compound Name
(R)-2-(4-(3-Cyano-5-fluorobenzoyl)piperazin-1-yl)-N-(2-cyclopropyl-2,2-difluoroethyl)-2-phenylacetamide
    Show/Hide
PubChem ID
CID: 145988400
Canonical SMILES
N#Cc1cc(F)cc(C(=O)N2CCN([C@@H](C(=O)NCC(F)(F)C3CC3)c3ccccc3)CC2)c1
    Show/Hide
Compound Formula C25H25F3N4O2
Compound Structure
Protein Name
Sodium channel protein type 9 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated sodium channel
Uniprot ID
Q62205
Gene Name
SCN9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 910 nM
   TI
   LI
   LO
   TS