Brief Information of the Compound and Protein
Compound Name
N-methyl-2-[[5-methyl-2-[3-(methylsulfonylmethyl)anilino]pyrimidin-4-yl]amino]benzamide
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PubChem ID
CID: 44526249
Canonical SMILES
CNC(=O)c1ccccc1Nc1nc(Nc2cccc(CS(C)(=O)=O)c2)ncc1C
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Compound Formula C21H23N5O3S
Compound Structure
Protein Name
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase WEE family
Uniprot ID
Q99640
Gene Name
PKMYT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 115 nM
   TI
   LI
   LO
   TS
2
Ki = 10.94 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 115 nM
2 IC50 = 151 nM
3 Ki = 10.94 nM