Brief Information of the Compound and Protein
Compound Name
2,6-difluoro-N-[3-[3-[2-(pyridin-3-ylamino)pyrimidin-4-yl]pyrazolo[1,5-b]pyridazin-2-yl]phenyl]benzamide
    Show/Hide
PubChem ID
CID: 44529068
Canonical SMILES
Fc1cccc(F)c1C(=O)Nc1cccc(c1)-c1nn2ncccc2c1-c1ccnc(Nc2cccnc2)n1
    Show/Hide
Compound Formula C28H18F2N8O
Compound Structure
Protein Name
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase WEE family
Uniprot ID
Q99640
Gene Name
PKMYT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 7560 nM
   TI
   LI
   LO
   TS
2
Ki = 720.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7560 nM
2 IC50 = 18880 nM
3 Ki = 720.2 nM