Brief Information of the Compound and Protein
Compound Name
 Compound Info 
AZD-1775
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 PubChem ID
CID: 24856436
SID: 50087297
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(-c2cccc(n2)C(C)(C)O)n(CC=C)c3=O)cc1
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Compound Formula C27H32N8O2
Compound Structure
Protein Name
 Protein Info 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase WEE family
Uniprot ID
Q99640
Gene Name
PKMYT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 4940 nM
   TI
   LI
   LO
   TS
2
Ki = 470 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 324 nM