Brief Information of the Compound and Protein
Compound Name
6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
    Show/Hide
PubChem ID
CID: 5311104
SID: 14905289
Canonical SMILES
Cc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)ccc1F
    Show/Hide
Compound Formula C21H15Cl2FN4O
Compound Structure
Protein Name
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase WEE family
Uniprot ID
Q99640
Gene Name
PKMYT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 109 nM
   TI
   LI
   LO
   TS
2
Ki = 10.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 109 nM
2 IC50 = 2700 nM
3 Ki = 10.4 nM