Brief Information of the Compound and Protein
Compound Name
(6aR)-4-(3,3,3-trifluoropropyl)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
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PubChem ID
CID: 134265732
Canonical SMILES
FC(F)(F)CCc1ccnc2N3CCNC[C@H]3CCc12
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Compound Formula C14H18F3N3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 1258.93 nM
   TI
   LI
   LO
   TS
2
EC50 = 1290 nM
   TI
   LI
   LO
   TS
3
Ki = 199.53 nM
   TI
   LI
   LO
   TS