Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpiperazin-1-yl)-2-piperazin-1-ylbenzimidazole
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 PubChem ID
CID: 145972055
Canonical SMILES
CN1CCN(CC1)c1cc(Cl)cc2n(Cc3cc(C)c(F)c(C)c3)c(nc12)N1CCNCC1
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Compound Formula C25H32ClFN6
Compound Structure
Protein Name
 Protein Info 
Son of sevenless homolog 1
Protein Classification
Unclassified protein
Uniprot ID
Q07889
Gene Name
SOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 6000 nM
   TI
   LI
   LO
   TS
CL000654 NCI-H727
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 7300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 140 nM