Brief Information of the Compound and Protein
Compound Name
6-chloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-ylbenzimidazole
    Show/Hide
PubChem ID
CID: 134814236
Canonical SMILES
Cc1n[nH]c(C)c1-c1cc(Cl)cc2n(Cc3cc(C)c(F)c(C)c3)c(nc12)N1CCNCC1
    Show/Hide
Compound Formula C25H28ClFN6
Compound Structure
Protein Name
Son of sevenless homolog 1
Protein Classification
Unclassified protein
Uniprot ID
Q07889
Gene Name
SOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 9000 nM
   TI
   LI
   LO
   TS
CL000654 NCI-H727 Homo sapiens (Human)  1
1
EC50 = 15600 nM
   TI
   LI
   LO
   TS