Brief Information of the Compound and Protein
Compound Name
5-[[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]methyl]-N-hydroxyfuran-2-carboxamide
    Show/Hide
PubChem ID
CID: 136645467
Canonical SMILES
CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(Cc2ccc(o2)C(=O)NO)ccc1OCC
    Show/Hide
Compound Formula C23H25N5O5
Compound Structure
Protein Name
cGMP-specific 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 5
>
Phosphodiesterase 5A
Uniprot ID
O76074
Gene Name
PDE5A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM