Brief Information of the Compound and Protein
Compound Name
N-[3-[(4S)-2-amino-4-(fluoromethyl)-6-methyl-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyanopyridine-2-carboxamide
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PubChem ID
CID: 78319724
Canonical SMILES
CC1=C[C@](CF)(N=C(N)O1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
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Compound Formula C19H15F2N5O2
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
IC50 = 17 nM
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