Brief Information of the Compound and Protein
Compound Name
N-[3-[(4S)-2-amino-6-(fluoromethyl)-4-methyl-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyano-3-methylpyridine-2-carboxamide
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PubChem ID
CID: 89974892
Canonical SMILES
Cc1cc(cnc1C(=O)Nc1ccc(F)c(c1)[C@]1(C)C=C(CF)OC(N)=N1)C#N
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Compound Formula C20H17F2N5O2
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
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Protease
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Aspartic protease
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Aspartic protease AA clan
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Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
IC50 = 8.4 nM
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