Brief Information of the Compound and Protein
Compound Name
N-(5-fluoropyridin-2-yl)-6-(5-fluoropyridin-3-yl)oxyquinoline-8-carboxamide
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PubChem ID
CID: 145964881
Canonical SMILES
Fc1ccc(NC(=O)c2cc(Oc3cncc(F)c3)cc3cccnc23)nc1
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Compound Formula C20H12F2N4O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 8 nM
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