Brief Information of the Compound and Protein
Compound Name
5-amino-8-(furan-2-yl)-1-methyl-3-[2-[4-[4-(oxolan-3-yloxy)phenyl]piperazin-1-yl]ethyl]-[1,2,4]triazolo[5,1-f]purin-2-one
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PubChem ID
CID: 56944358
SID: 135646660
Canonical SMILES
Cn1c2c(nc(N)n3nc(nc23)-c2ccco2)n(CCN2CCN(CC2)c2ccc(OC3CCOC3)cc2)c1=O
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Compound Formula C27H31N9O4
Compound Structure
Protein Name
Adenosine receptor A2a
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P29274
Gene Name
ADORA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 0.2 nM
   TI
   LI
   LO
   TS
2
Ki = 0.22 nM
   TI
   LI
   LO
   TS