Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[1-[[(3S)-2-hydroxy-5-oxooxolan-3-yl]amino]-1-oxobutan-2-yl]-2,4-dioxo-1-propan-2-ylpyrimidin-5-yl]-3-methyl-5-(naphthalen-2-ylamino)pyridine-2-carboxamide
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 PubChem ID
CID: 145977507
Canonical SMILES
CCC(C(=O)N[C@H]1CC(=O)OC1O)n1c(=O)c(NC(=O)c2ncc(Nc3ccc4ccccc4c3)cc2C)cn(C(C)C)c1=O
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Compound Formula C32H34N6O7
Compound Structure
Protein Name
 Protein Info 
Caspase-1
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
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Cysteine protease CD clan
>
Cysteine protease C14 family
Uniprot ID
P29466
Gene Name
CASP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 200 nM
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