Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[1-[[(3S)-2-hydroxy-5-oxooxolan-3-yl]amino]-1-oxopropan-2-yl]-1-methyl-2,4-dioxopyrimidin-5-yl]-4-(quinoxalin-2-ylamino)benzamide
    Show/Hide
 PubChem ID
CID: 145966058
Canonical SMILES
CC(C(=O)N[C@H]1CC(=O)OC1O)n1c(=O)c(NC(=O)c2ccc(Nc3cnc4ccccc4n3)cc2)cn(C)c1=O
    Show/Hide
Compound Formula C27H25N7O7
Compound Structure
Protein Name
 Protein Info 
Caspase-1
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CD clan
>
Cysteine protease C14 family
Uniprot ID
P29466
Gene Name
CASP1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 31.62 nM