Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 4-(3'-ethyl-6-fluorobiphenyl-2-yl)-4-hydroxy-4-((R)-1-(4-(2-hydroxyethylamino)butanoyl)piperidin-3-yl)butylcarbamate
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 PubChem ID
CID: 59620457
Canonical SMILES
CCc1cccc(-c2c(F)cccc2C(O)(CCCNC(=O)OC)[C@@H]2CCCN(C(=O)CCCNCCO)C2)c1
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Compound Formula C31H44FN3O5
Compound Structure
Protein Name
 Protein Info 
Renin
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P00797
Gene Name
REN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 63 nM