Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-methyl 2-amino-5-((3R)-3-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-4-(methoxycarbonylamino)butyl)piperidin-1-yl)-5-oxopentanoate
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 PubChem ID
CID: 145966339
Canonical SMILES
CCc1cccc(-c2c(F)cccc2C(O)(CCCNC(=O)OC)[C@@H]2CCCN(C(=O)CC[C@H](N)C(=O)OC)C2)c1
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Compound Formula C31H42FN3O6
Compound Structure
Protein Name
 Protein Info 
Renin
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P00797
Gene Name
REN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 540 nM