Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl N-[4-[2-(3-ethylphenyl)-3-fluorophenyl]-4-hydroxy-4-[(3R)-1-[2-(methylamino)ethylcarbamoyl]piperidin-3-yl]butyl]carbamate
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 PubChem ID
CID: 91349601
Canonical SMILES
CCc1cccc(c1)-c1c(F)cccc1C(O)(CCCNC(=O)OC)[C@@H]1CCCN(C1)C(=O)NCCNC
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Compound Formula C29H41FN4O4
Compound Structure
Protein Name
 Protein Info 
Renin
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P00797
Gene Name
REN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 120 nM