Brief Information of the Compound and Protein
Compound Name
(3R)-3-benzyl-4-[cyclopropyl-[4-(2,5-dichlorophenyl)-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid
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PubChem ID
CID: 53302677
SID: 124760257
Canonical SMILES
OC(=O)C[C@@H](Cc1ccccc1)C(=O)N(C1CC1)c1nc(cs1)-c1cc(Cl)ccc1Cl
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Compound Formula C23H20Cl2N2O3S
Compound Structure
Protein Name
Free fatty acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O15552
Gene Name
FFAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 12.59 nM
   TI
   LI
   LO
   TS
2
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 208.93 nM
   TI
   LI
   LO
   TS