Brief Information of the Compound and Protein
Compound Name
(3R)-3-(cyclopentylmethyl)-4-[cyclopropyl-[4-[2-(6-methoxypyridin-3-yl)phenyl]-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid
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PubChem ID
CID: 67209751
Canonical SMILES
COc1ccc(cn1)-c1ccccc1-c1csc(n1)N(C1CC1)C(=O)[C@H](CC1CCCC1)CC(O)=O
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Compound Formula C28H31N3O4S
Compound Structure
Protein Name
Free fatty acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O15552
Gene Name
FFAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 25.12 nM
   TI
   LI
   LO
   TS
2
Ki = 158.49 nM
   TI
   LI
   LO
   TS