Brief Information of the Compound and Protein
Compound Name
N-(6-(4-(2-hydroxybenzyl)piperazin-1-yl)pyridin-3-yl)-2-(trifluoromethyl)benzamide
    Show/Hide
PubChem ID
CID: 46053738
Canonical SMILES
O=C(Nc1ccc(N2CCN(Cc3ccccc3O)CC2)nc1)c1ccccc1C(F)(F)F
    Show/Hide
Compound Formula C24H23F3N4O2
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS