Brief Information of the Compound and Protein
Compound Name
1-(4-fluorophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)piperidin-4-ylamino)pyrrolidine-2,5-dione
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PubChem ID
CID: 5299952
Canonical SMILES
O=C1CC(NC2CCN(c3ccc(C(F)(F)F)cn3)CC2)C(=O)N1c1ccc(F)cc1
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Compound Formula C21H20F4N4O2
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
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